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The Huntington Center welcomes HD researchers and clinicians in the Nordic countries to a one-day Nordic Huntington Disease Research Meeting in Lund Nov 26, 2019

The 2nd Nordic HD Research Meeting will take place on Tuesday November 26, 2019 in the Belfrage hall at D15 of the Biomedical Center (BMC), Klinikgatan 32, in Lund, Sweden. It is organized by the Huntington Center and is open to HD researchers and clinicians in the Nordic countries.
There will be a large number of data blitz presentations to allow for both PI’s, postdoctoral fellows and PhD students to present their work and then ample time over lunch, breaks and dinner to interact. There will be an update on clinical trials and activities of the European HD Network (EHDN). The official language will be English.

Registration for this event is now closed.


09.30-10.00 Registration and coffee

10.00-10.15 Welcome and presentation of the Huntington Disease Center (chair Åsa Petersén, Lund)

10.15-11.00 Data blitz presentations- Clinical research (10 min + 5 min Q&A; chair Lena Hjermind, Copenhagen)

10.15-10.30 Distribution of CAG repeats in Northern Sweden (Valter Niemelä, Uppsala)

10.30-10.45 Huntington’s disease and proteomics (Niels Henning Skotte, Copenhagen)

10.45-11.00 Modelling Huntington’s disease using directly reprogrammed patient-derived neurons (Karolina Pircs, Lund

11.00-11.40 The role of the ubiquitin/proteasome system in the development of CAG triplet repeat disorders (Nico Dantuma, Stockholm; chair Åsa Petersén, Lund)

11.40-12.45 Lunch

12.45-14.00 Data blitz presentations - Mechanisms of disease (10 min + 5 min Q&A; chair Nico Dantuma, Stockholm)

12:45-13.00 Dynamic interaction of USP14 with HSC70 influences autophagy in HD (Vignesh Srinivasan, Helsinki)

13.00-13.15 Whole genome sequencing of HD families to identify novel rare variants that modify age of onset (Kristina Becanovic, Stockholm)

13.15-13.30 Satellite progenitor cell dysfunction in the R6/2 mouse model of Huntington disease (Rana Soylu-Kucharz, Lund)

13.30-13.45 HD cell models for studies of cellular and synaptic antioxidant systems (Luisana Carolina Duque Villegas, Copenhagen)

13.45-14.00 Effects of wild-type huntingtin protein expression in the hypothalamus of R6/2 and BACHD animal models (Elna Dickson, Lund)

14.00-14.30 Coffee break

14.30-15.30 Data blitz presentations - Future therapies (10 min + 5 min Q&A , chair Merja Voutilainen, Helsinki)

14.30-14.45 Effect of CDNF in animal models of Huntington`s disease (Polina Stepanova, Helsinki)

14.45-15.00 Role of the oxytocin-vasopressin system in Huntington's disease (Rachel Y Cheong, Lund)

15.00-15.15 First in class SORCS modulators for Huntington disease (Simon Molgaard, Aarhus)

15.15-15.30 CRISPR baser RNA therapy in a human model of Huntington's disease (Dzeneta Vizlin Hodzic, Gothenburg)

15.30-15.50 Break

15.50-16.45 Update on the activities of the European HD Network (EHDN) and clinical trials in Europe by EHDN co-chair Patrick Weydt, Bonn (chair Maria Björkqvist, Lund)

16.45-17.15 European HD Association and research by President of EHA Astri Arnesen, Norway (chair Åsa Petersén, Lund)

17.15-17.30 Final discussion (chairs Åsa Petersén and Maria Björkqvist, Lund)

18.00- 21.00 Networking and Meeting Dinner at Restaurant På Skissernas, Finngatan 2, Lund

Warm welcome!

Åsa Petersén, on behalf of the Huntington Center in Lund

Organizing committee: Maria Björkqvist, Jenny Månsson and Åsa Petersén.