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Former team members

Jo Beldring Henningsen

Former Postdoctoral fellow in TNU, 2016-2018.

Publications from TNU:

Baldo B, Gabery S, Soylu-Kucharz R, Cheong RY, Henningsen JB, Englund E, McLean C, Kirik D, Halliday G and Petersén Å.
SIRT1 is increased in affected brain regions and hypothalamic metabolic pathways are altered in Huntington disease.
Neuropathology and Applied Neurobiology. 2018 Jul 18. doi: 10.1111/nan.12514. [Epub ahead of print]


Barbara Baldo

Former Postdoctoral fellow in TNU, 2012-2017.

Publications from TNU:

Soylu-Kucharz R, Baldo B and Petersén Å.
Metabolic and behavioral effects of mutant huntingtin deletion in Sim1 neurons in the BACHD mouse model of Huntington's disease.
Scientific Reports 6: 28322 (2016)

Soylu-Kucharz R, Adlesic N, Baldo B, Kirik D and Petersén Å.
Hypothalamic overexpression of mutant huntingtin causes dysregulation of brown adipose tissue.
Sci Rep. 2015 Sep 30;5:14598

Baldo B and Petersén Å.
Analysis of nonmotror features in murine models of Huntington disease.
In MS LeDoux (Ed): Movement Disorders 35: 584-597. Elsevier (2015)

Baldo B, Cheong RY and Petersén Å.
Effects of Deletion of Mutant Huntingtin in Steroidogenic Factor 1 Neurons on the Psychiatric and Metabolic Phenotype in the BACHD Mouse Model of Huntington Disease.
PLoS One 9(10): 1-10 (2014)

Baldo B, Soylu R and Petersén Å.
Maintenance of Basal Levels of Autophagy in Huntington’s Disease Mouse Models Displaying Metabolic Dysfunction.
PLoS One 8(12) (2013)


Sanaz Gabery

Former PhD student in TNU; PhD defence date 2015-05-13.

Publications from TNU:

Gabery S, Georgiou-Karistianis N, Lundh SH, Cheong RY, Churchyard A, Chua P, Stout JC, Egan GF, Kirik D and Petersén Å.
Volumetric Analysis of the Hypothalamus in Huntington Disease Using 3T MRI: The IMAGE-HD Study.
PLoS One. 2015 Feb 6;10(2):e0117593.

Gabery S, Sajjad MU, Hult S, Soylu R, Kirik D and Petersén Å.
Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.
European Journal of Neuroscience 36(6):2789-800 (2012).

Petersen Å and Gabery S.
Hypothalamic and limbic system changes in Huntington's disease.
Journal of Huntington's disease 1: 13-24 (2012).

Piguet O, Petersén A, Yin Ka Lam B, Gabery S, Murphy K, Hodges JR and Halliday GM. 
Eating and hypothalamus changes in behavioral-variant frontotemporal dementia. 
Annals of Neurology 69: 312-319 (2011).

Gabery S, Murphy K, Schultz K, Loy CT, McCusker E, Kirik D, Halliday G and Petersén Å.
Changes in key hypothalamic neuropeptide populations in Huntington disease revealed by neuropathological analyses. 
Acta Neuropathologica 120: 777-788 (2010)


Sofia Hult Lundh

Former PhD student in TNU; PhD defence date 2014-05-28.

Publications from TNU:

Gabery S, Georgiou-Karistianis N, Lundh SH, Cheong RY, Churchyard A, Chua P, Stout JC, Egan GF, Kirik D and Petersén Å.
Volumetric Analysis of the Hypothalamus in Huntington Disease Using 3T MRI: The IMAGE-HD Study.
PLoS One 10(2): 1-18 (2015)

Hult Lundh S, Nilsson N, Soylu R, Kirik D and Petersén Å.
Hypothalamic expression of mutant huntingtin contributes to the development of depressive-like behavior in the BAC transgenic mouse model of Huntington's disease.
Human Molecular Genetics 22: 3485-3497 (2013)

Lundh SH, Soylu R and Petersén Å.
Expression of Mutant Huntingtin in Leptin Receptor-Expressing Neurons Does Not Control the Metabolic and Psychiatric Phenotype of the BACHD Mouse. 
PLoS One 7(12): 1-9 (2012)

Gabery S, Sajjad MU, Hult S, Soylu R, Kirik D and Petersén Å.
Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.
European Journal of Neuroscience 36(6): 2789-800 (2012)

Hult S*, Soylu R*, Björklund T, Belgardt BF, Mauer J, Brüning JC, Kirik D and Petersén Å.
Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits.
Cell Metabolism 13: 428-439 (2011) *equal contribution

Hult S, Schultz K, Soylu R and Petersén Å.
Hypothalamic and Neuroendocrine Changes in Huntington's Disease.
Current Drug Targets 11: 1237-1249 (2010)


Muhammad Umar Sajjad

Former Postdoctoral fellow in TNU, 2011-2013.

Publications from TNU:

Gabery S, Sajjad MU, Hult S, Soylu R, Kirik D and Petersén Å.
Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors.
European Journal of Neuroscience 36(6): 2789-800 (2012)


Yongxia Zhou

Former Postdoctoral fellow in TNU, 2010.

Publications from TNU:

Soneson C, Fontes M, Zhou Y, Denisov V, Paulsen JS, Kirik D and Petersén Å; The Huntington Study Group PREDICT-HD investigators.
Early changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis.  
Neurobiology of Disease 40: 531-543 (2010)

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Translational Neuroendocrine Research Unit
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