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Translational Research Laboratory

Translational studies addressing the main aims of the research group use experimental models and clinical material from patients with HD and FTD/ALS. Techniques used in the laboratory include detailed testing of motor, cognitive, social/emotional behaviours, metabolic function, stereotactic surgery, gene targeting and disease modelling using adeno-associated viral vectors (AAV), immunohistochemistry, stereology, ELISA, RIA, Western blots, HPLC, RT-PCR as well as MRI analysis.
 

 

Illustration of a brain and the genes affecting HD and FTD/ALS. Original by Sanaz Gabery.

Illustration by Sanaz Gabery