Åsa Petersén, Sanaz Gabery and collaborators in Australia have, for the first time, shown changes in hypothalamic neurons regulating metabolism, sleep and emotions in ALS patients.
Since long, researchers have assumed that changes in metabolism are affecting the progress of the disease. Identification of the underlying neurobiological mechanisms may contribute to new treatments for ALS in the future.
The results of the study reveal specific changes in the hypothalamus that may play a role in causing altered metabolism, sleep problems and dysregulation of emotions in ALS.
Read the article on Lund University's webpage. In Swedish only.